Health benefits of vitamin C
Because of its widespread use as a
dietary supplement, vitamin C may be more familiar to the general public than
any other nutrient. Studies indicate that more than 40% of older individuals in
the U.S. take vitamin C supplements; and in some regions of the country, almost
25% of all adults, regardless of age, take vitamin C. Outside of a
multivitamin, vitamin C is also the most popular supplement among some groups
of registered dietitians, and 80% of the dietitians who take vitamin C take
more than 250 milligrams.
Why is this nutrient so popular?
Vitamin C, also called ascorbic
acid, is a water-soluble nutrient that is easily excreted from the body when
not needed. It's so critical to living creatures that almost all mammals can
use their own cells to make it. Humans, gorillas, chimps, bats, guinea pigs and
birds are some of the few animals that cannot make vitamin C inside of their
own bodies.
Humans vary greatly in their vitamin
C requirement. It's natural for one person to need 10 times as much vitamin C as
another person; and a person's age and health status can dramatically change
his or her need for vitamin C. The amount of vitamin C found in food varies as
dramatically as our human requirement. In general, an unripe food is much lower
in vitamin C than a ripe one, but provided that the food is ripe, the vitamin C
content is higher when the food is younger at the time of harvest.
How it Functions
What is the function of vitamin C?
Vitamin C serves a predominantly
protective role in the body. As early as the 1700's, vitamin C was referred to
as the "antiscorbutic factor," since it helped prevent the disease
called scurvy. This disease was first discovered in British sailors, whose sea
voyages left them far away from natural surroundings for long periods of time.
Their body stores of vitamin C fell below 300 milligrams, and their gums and
skin lost the protective effects of vitamin C. Recognizing limes as a good
shipboard source of vitamin C, the British sailors became known as
"limeys" for carrying large stores of limes aboard ship.
The protective role of vitamin C
goes far beyond our skin and gums. Cardiovascular diseases, cancers, joint
diseases and cataracts are all associated with vitamin C deficiency and can be
partly prevented by optimal intake of vitamin C. Vitamin C achieves much of its
protective effect by functioning as an antioxidant and preventing oxygen-based
damage to our cells. Structures that contain fat (like the lipoprotein
molecules that carry fat around our body) are particularly dependent on vitamin
C for protection.
Deficiency Symptoms
What are deficiency symptoms for
vitamin C?
Full-blown symptoms of the vitamin C
deficiency disease called scurvy—including bleeding gums and skin discoloration
due to ruptured blood vessels—are rare in the U.S. Poor wound healing, however,
is not rare, and can be a symptom of vitamin C deficiency. Weak immune
function, including susceptibility to colds and other infections, can also be a
telltale sign of vitamin C deficiency. Since the lining of our respiratory
tract also depend heavily on vitamin C for protection, respiratory infection
and other lung-related conditions can also be symptomatic of vitamin C
deficiency.
Toxicity Symptoms
What are toxicity symptoms for
vitamin C?
There are very few research studies
that document vitamin C toxicity at any level of supplementation, and there are
no documented toxicity effects whatsoever for vitamin C in relation to food and
diet. At high supplemental doses involving 5 or more grams of vitamin C,
diarrhea can result from the fluid in the intestine becoming too concentrated
("osmotic diarrhea").
Large supplemental doses of vitamin
C can also increase levels of uric acid in the urine, because vitamin C can be
broken down into uric acid. However, it is not clear that increased uric acid
in the urine can increase a person's risk of forming uric acid kidney stones.
Finally, vitamin C can increase a
person's absorption of iron from plant foods; and persons who
have health problems related to excess free iron in their cells may want to
consider avoiding high supplemental doses of vitamin C. It is important to
remember that all of the above toxicity-related issues involve vitamin C in
supplemental form, not as it naturally occurs in food.
In 2000, the National Academy of
Sciences set a Tolerable Upper Intake Level (UL) for vitamin C at 2,000
milligrams (2 grams) for adults 19 years or older.
Impact of Cooking, Storage and
Processing
How do cooking, storage, or
processing affect vitamin C?
Vitamin C is highly sensitive to
air, water, and temperature. About 25% of the vitamin C in vegetables can be
lost simply by blanching (boiling or steaming the food for a few minutes). This
same degree of loss occurs in the freezing and unthawing of vegetables and
fruits. Cooking of vegetables and fruits for longer periods of time (10-20
minutes) can result in a loss of over one half the total vitamin C content.
When fruits and vegetables are canned and then reheated, only 1/3 of the
original vitamin C content may be left. Consumption of vitamin C-rich foods in
their fresh, raw form is the best way to maximize vitamin C intake.
Factors that Affect Function
What factors might contribute to a
deficiency of vitamin C?
Poor intake of vitamin C-rich
vegetables and fruits is a common contributor to vitamin C deficiency. In the
U.S., one third of all adults get less vitamin C from their diet than is
recommended by the National Academy of Sciences, and 1 out of every 6 adults
gets less than half the amount recommended. Smoking and exposure to second hand
smoke also increase the risk of vitamin C deficiency.
The body's immune and detoxification
systems make special use of vitamin C, and overload in either of these systems
can increase risk of deficiency. The immune system relies on a wide variety of
mechanisms to help protect the body from infection, including white blood
cells, complement proteins, and interferons; and vitamin C is especially
important in the function of these immune components.
Vitamin C is also critical during
the first phase of the body's detoxification process. This process occurs in
many types of tissue, but it is especially active in the liver. When the body
is exposed to toxins, vitamin C is often required for the body to begin
processing the toxins for elimination. Excessive toxic exposure is therefore a
risk factor for vitamin C deficiency.
Nutrient Interactions
What health conditions require
special emphasis on vitamin C?
Most forms of cardiovascular
disease, joint disease, cancer, eye disease, thyroid disease, liver disease,
and lung disease require special emphasis on vitamin C intake. The process of
aging itself requires special attention to vitamin C. In addition to these
broader categories, several specific health conditions also require special
emphasis on vitamin C. These specific health conditions include:
- Acne
- Alcoholism
- Alzheimer's
disease
- Asthma
- Autism
- Depression
- Diabetes
- Irritable
bowel disease
- Parkinson's disease
World's Healthiest Foods ranked as
quality sources of
vitamin C |
||||||
Food
|
Serving
Size |
Cals
|
Amount
(mg) |
DV
(%) |
Nutrient
Density |
World's
Healthiest Foods Rating |
Papaya
|
1 each
|
118.6
|
187.87
|
313.1
|
47.5
|
excellent
|
Bell Peppers
|
1 cup raw
|
28.5
|
117.48
|
195.8
|
123.6
|
excellent
|
Strawberries
|
1 cup
|
46.1
|
84.67
|
141.1
|
55.1
|
excellent
|
Broccoli
|
1 cup raw
|
30.9
|
81.17
|
135.3
|
78.7
|
excellent
|
Pineapple
|
1 cup
|
82.5
|
78.87
|
131.4
|
28.7
|
excellent
|
Brussels Sprouts
|
1 cup raw
|
37.8
|
74.80
|
124.7
|
59.3
|
excellent
|
Kiwifruit
|
1 each
|
45.0
|
72.00
|
120.0
|
48.0
|
excellent
|
Oranges
|
1 each
|
61.6
|
69.69
|
116.2
|
34.0
|
excellent
|
Cantaloupe
|
1 cup
|
54.4
|
58.72
|
97.9
|
32.4
|
excellent
|
Kale
|
1 cup cooked
|
36.4
|
53.30
|
88.8
|
43.9
|
excellent
|
Cauliflower
|
1 cup raw
|
26.8
|
51.57
|
86.0
|
57.8
|
excellent
|
Grapefruit
|
0.50 each
|
41.0
|
44.03
|
73.4
|
32.2
|
excellent
|
Turnip Greens
|
1 cup cooked
|
28.8
|
39.46
|
65.8
|
41.1
|
excellent
|
Mustard Greens
|
1 cup cooked
|
21.0
|
35.42
|
59.0
|
50.6
|
excellent
|
Collard Greens
|
1 cup cooked
|
49.4
|
34.58
|
57.6
|
21.0
|
excellent
|
Raspberries
|
1 cup
|
64.0
|
32.23
|
53.7
|
15.1
|
excellent
|
Swiss Chard
|
1 cup cooked
|
35.0
|
31.50
|
52.5
|
27.0
|
excellent
|
Lemons and Limes, Juice
|
0.25 cup
|
15.2
|
28.06
|
46.8
|
55.2
|
excellent
|
Cabbage
|
1 cup raw
|
17.5
|
25.62
|
42.7
|
43.9
|
excellent
|
Tomatoes
|
1 cup raw
|
32.4
|
22.86
|
38.1
|
21.2
|
excellent
|
Romaine Lettuce
|
2 cups
|
16.0
|
22.56
|
37.6
|
42.4
|
excellent
|
Winter Squash
|
1 cup baked
|
75.8
|
19.68
|
32.8
|
7.8
|
excellent
|
Summer Squash
|
1 cup raw
|
18.1
|
19.21
|
32.0
|
31.9
|
excellent
|
Spinach
|
1 cup cooked
|
41.4
|
17.64
|
29.4
|
12.8
|
excellent
|
Watermelon
|
1 cup
|
45.6
|
12.31
|
20.5
|
8.1
|
excellent
|
Green Beans
|
1 cup raw
|
31.0
|
12.20
|
20.3
|
11.8
|
excellent
|
Fennel
|
1 cup raw
|
27.0
|
10.44
|
17.4
|
11.6
|
excellent
|
Parsley
|
2 tbs
|
2.7
|
10.11
|
16.9
|
110.7
|
excellent
|
Asparagus
|
1 cup raw
|
26.8
|
7.50
|
12.5
|
8.4
|
excellent
|
Cranberries
|
0.50 cup
|
23.0
|
6.65
|
11.1
|
8.7
|
excellent
|
Sweet Potato
|
1 cup baked
|
102.6
|
22.34
|
37.2
|
6.5
|
very good
|
Green Peas
|
1 cup raw
|
115.7
|
19.56
|
32.6
|
5.1
|
very good
|
Blueberries
|
1 cup
|
84.4
|
14.36
|
23.9
|
5.1
|
very good
|
Onions
|
1 cup raw
|
64.0
|
11.84
|
19.7
|
5.6
|
very good
|
Leeks
|
1 cup raw
|
54.3
|
10.68
|
17.8
|
5.9
|
very good
|
Carrots
|
1 cup
|
50.0
|
7.20
|
12.0
|
4.3
|
very good
|
Beets
|
1 cup raw
|
58.5
|
6.66
|
11.1
|
3.4
|
very good
|
Plum
|
1 each
|
30.4
|
6.27
|
10.4
|
6.2
|
very good
|
Garlic
|
1 oz-wt
|
26.8
|
5.62
|
9.4
|
6.3
|
very good
|
Apricot
|
1 each
|
16.8
|
3.50
|
5.8
|
6.2
|
very good
|
Cloves
|
2 tsp
|
13.6
|
3.39
|
5.7
|
7.5
|
very good
|
Celery
|
1 cup
|
16.2
|
3.13
|
5.2
|
5.8
|
very good
|
Potatoes
|
1 each baked
|
160.9
|
16.61
|
27.7
|
3.1
|
good
|
Yam
|
1 cup baked
|
157.8
|
16.46
|
27.4
|
3.1
|
good
|
Avocado
|
1 cup
|
233.6
|
14.60
|
24.3
|
1.9
|
good
|
Banana
|
1 each
|
105.0
|
10.27
|
17.1
|
2.9
|
good
|
Apple
|
1 small
|
94.6
|
8.37
|
13.9
|
2.7
|
good
|
Corn
|
1 cup
|
143.0
|
8.20
|
13.7
|
1.7
|
good
|
Pear
|
1 each
|
103.2
|
7.48
|
12.5
|
2.2
|
good
|
Grapes
|
1 cup
|
61.6
|
3.68
|
6.1
|
1.8
|
good
|
Cucumber
|
1 cup
|
15.6
|
2.91
|
4.8
|
5.6
|
good
|
Cayenne Pepper
|
2 tsp
|
11.4
|
2.75
|
4.6
|
7.2
|
good
|
Peppermint
|
2 tbs
|
5.3
|
2.42
|
4.0
|
13.6
|
good
|
Eggplant
|
1 cup raw
|
19.7
|
1.80
|
3.0
|
2.7
|
good
|
Basil
|
2 tsp
|
7.0
|
1.71
|
2.9
|
7.3
|
good
|
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